Drug
Therapies for Rheumatoid Arthritis
Rheumatoid arthritis is a progressive disease that affects
over two million Americans. Symptoms may include joint
stiffness, muscle ache, and general discomfort. As a
progressive disease, it is expected that most patients will
experience a worsening of symptoms as time progress.
Fortunately, there are many drug therapies available to
patients that can help alleviate the patient's symptoms
considerably. The primary goal of therapy consists of helping
alleviate the symptoms associated with rheumatoid arthritis so
that the patient can take part in all their normal activities
with as little pain or discomfort as possible.
Sometimes, the patient may have to learn to modify their
activities in order to prevent damage or discomfort. For the
most part, however, individuals with rheumatoid arthritis can
lead healthy lives. Drug therapies are prescribed according to
each individual's specific circumstances and symptoms. Many
times, two or more drug therapies are used in conjunction with
one another to achieve the best possible results.
Traditional drug therapies consist of anti-inflammatory
drugs. These are often referred to as NSAIDs. NSAIDs are
non-steroidal and are targeted at reducing mild to moderate
symptoms associated with inflammation caused by rheumatoid
arthritis. For more advanced cases of rheumatoid arthritis,
doctors often prescribe a specific class of drugs, often
referred to as DMARDs. These are also known as
disease-modifying antirheumatic drugs, sometimes also referred
to as glucocorticoids. DMARDs should ideally be prescribed at
the early stages of treatment.
Research has shown that DMARDs are most effective when
indicated at the beginning of treatment. In fact, DMARD drugs
tend to be avoided for advanced cases of rheumatoid arthritis
because they have been shown to cause serious side effects. If
prescribed early enough, DMARDs have been shown effective at
relieving signs of joint damage.
The conventional approach to treating rheumatoid arthritis
with drugs consists of prescribing DMARD drugs to the patients
as early as possible after a positive diagnosis. Studies
indicate that if a patient is treated approximately three to
twelve moths after the symptoms of rheumatoid arthritis have
been first noticed the patient has a considerably greater
chance of going into remission. DMARD drugs are effective at
fighting the inflammation associated with rheumatoid arthritis,
and can slow the progress of the disease considerably when
treatment is offered early enough. With their ability to ease
the patient into remission, DMARD class drugs are generally
regarded as the most effective treatment option for rheumatoid
arthritis patients.
In general DMARDs can take up to two to three months to take
maximum effect. DMARDs can be used in conjunction with other
types of drug therapies. However, most patients find that the
need for other anti-inflammatory drugs is greatly reduced or
even eliminated. Although DMARDs are not a magical solution
that works for everyone, they have proven effective in helping
millions of rheumatoid arthritis sufferers enter remission or
at least experiencing a substantial lessening of symptoms. For
most patients, DMARDs are prescribed on a long-term basis. This
is true of most drug therapies that are currently available to
rheumatoid arthritis patients.
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